
Now for some good news on the golden retriever health front.
We soon may be able to screen for sensory ataxic neuropathy in golden retrievers. This disorder is not terribly common in golden retrievers, but affected dogs have severe deficits in motor coordination and sensory perception. A dog with this disorder is not going to be able to run and play, and it certainly will be of no use as a working dog or dog sport competitor. (I think this disorder is limited to European strain goldens, but I could be wrong.)
The disorder was traced to a mutation in the mitochondrial DNA. It turns out that all dogs that have this disorder trace their lineage to a single female dog that lived in the 1970’s. Because it appeared to be maternally inherited, the researchers examined the mtDNA sequences of these dogs. It turns out that affected dogs have had one base pair deletion in the mitochondrial tRNA-Tyr gene. This mutation causes the mitochondria (the engine of the cells) to malfunction, and the dogs start losing neurons as they mature.
Because the gene has been identified, it will soon be possible to screen dogs for that mutation. Then breeders can select breeding stock that are free of that mutation, thereby producing dogs that no longer have sensory ataxic neuropathy.
This is good news for golden retriever health and for dog health in general. The more precise screenings we have for the genes that cause these inherited disorders the better. If only all of these inherited diseases were caused by easily identifiable genes, then we would be able to really breed healthy animals without much worry. However, life is not that simple.




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They may be gone already, because I was going to try the adsense “reporting a violation” although I didn’t see any ads (perhaps they’ve been caught, and when I tried to type it into my URL address box, it came up with some words but no blog (I didn’t understand the meaning of the words — I’m too new at the internet– “index of” and then some code, perhaps).
What irked me about that site, besides the thievery, was that there was no contact links to the original site and hence no way to get more information, make comments, etc. I saw your article but did not know it was with wordpress.
Is this ataxia apparent at an early age? My older dog (mixed breed — one of his breeds could be golden retreiver — it’s not apparent in his picture, but he has a golden tint to his back hair and it is curly) has developed the disorder just this year. The vets are calling it idiopathic vestibular disorder, right now, though we’ve done some tests.
This ataxia happens when they are very young– often starting before they are four months old.
I don’t know whether it exists in the US golden retriever population or not.
I’m not a vet, so I really don’t know what could be affecting your dog. Usually, these genetic disorders are diluted when you have multiple crosses that make up a dog’s pedigree.